ncRNA name | hsa-miR-140-5p |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples; RB cell lines |
Methods | qRT-PCR, Western blot, CCK-8 assay, Edu staining, colony formation assay, flow cytometry, wound-healing assay and transwell assay, immunofluorescence, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | Overexpression of miR-140-5p inhibited proliferation, migration, and invasion of RB cells. miR-140-5p might negatively regulate the transcriptional activities of CEMIP and CADM3 by targeting their 3'-UTR. |
PubMed ID | 29808799 |
Year | 2018 |
Title | miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3. |
Drug-related ncRNA | NO |
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